Advacan - 0.5 Tablet

1. Medical Uses

Everolimus 0.5 mg is an mTOR inhibitor used under strict medical supervision for:

• Prevention of organ transplant rejection (kidney or liver) in combination with other immunosuppressants

• Advanced kidney cancer (RCC)

• Subependymal giant cell astrocytoma (SEGA) associated with tuberous sclerosis

• Renal angiomyolipoma in tuberous sclerosis

• Certain hormone receptor–positive breast cancers (as part of combination therapy)

• Neuroendocrine tumors of the pancreas, GI tract, or lungs (depending on protocol)

It works by slowing abnormal cell growth and reducing immune activity.

2. Dosage (General Medical Information Only)

• Dose depends on medical condition, treatment plan, body response, and blood levels.

• Often taken once daily, around the same time every day.

• Dose adjustments are made based on blood tests, renal function, liver function, and other medications.

Only a specialist (oncologist or transplant physician) should set or adjust the dosage.

3. Possible Side Effects

Common side effects may include:

• Mouth sores or ulcers

• Fatigue

• Nausea

• Swelling of legs

• Acne or rash

• Increased cholesterol or blood sugar

• Low blood counts

More serious effects can occur depending on overall health and treatment duration. Any unusual symptoms should be reported to a doctor immediately.

4. How to Use

• Take the tablet whole with water; do not crush or chew.

• Take at the same time daily, with or without food (but be consistent).

• Avoid grapefruit or grapefruit juice, as it interferes with the medicine.

• Regular blood tests are required to monitor drug levels and organ function.

• Follow all instructions given by your doctor or transplant/oncology team.