Naphcel 100 mg

Medical Uses

Doxycycline injection is a broad-spectrum antibiotic used when oral doxycycline cannot be given, or when a rapid effect is needed. It is used for:

• Severe bacterial infections

• Respiratory tract infections (pneumonia, atypical infections)

• Skin and soft tissue infections

• Severe acne-related infections

• Intra-abdominal infections

• Tick-borne infections such as:

  • Scrub typhus

  • Rocky Mountain spotted fever

  • Lyme disease

• Sexually transmitted infections

• Malaria (combination therapy)

• Anthrax (including inhalational anthrax)

Dosage (Doctor Must Decide)

Typical adult dosing:

Standard Dose

• 100 mg IV every 12 hours on Day 1

• Then 100 mg IV once daily

• For severe infections: 100 mg IV every 12 hours may be continued

Route

• IV infusion only

• Not given as IM (intramuscular), as it causes severe tissue irritation

Dilution and Infusion

• Reconstituted with sterile water

• Further diluted and infused over 1–4 hours depending on dose

Dosage adjustments may be required for special conditions.

Side Effects

Common:

• Nausea

• Diarrhea

• Injection site pain or inflammation

• Skin sensitivity to sunlight

Less common:

• Liver enzyme elevation

• Low blood pressure during infusion (rare)

• Tooth discoloration (avoid in children under 8 unless essential)

Serious (seek medical care):

• Severe allergic reaction

• Severe headache/visual changes (possible intracranial hypertension)

• Persistent diarrhea (C. difficile risk)

How to Use

• Administered only by trained healthcare professionals

• Given as slow IV infusion, never as IV push

• Monitoring required for:

  • Allergic reactions

  • Blood pressure during infusion

  • Liver and kidney function

  • Gastrointestinal symptoms

Patients should avoid excessive sun exposure during treatment.